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Nix (gene) Nix is a pro-apoptotic gene that is regulated by hypoxia. It expresses a signaling protein related to the BH3-only family. This protein induces autophagy, an intracellular function by which cytoplasmic components are delivered to the lysosome to be broken down and used elsewhere or excreted from the cell.〔Zhang, Ji, and Paul A. Ney. “ROLE OF BNIP3 AND NIX IN CELL DEATH, AUTOPHAGY, AND MITOPHAGY.” Cell death and differentiation 16.7 (2009): 939–946. PMC. Web. 15 Apr. 2015.〕 This protein is important in development because it allows cells to have a consistent store of cellular components. 〔Mizushima, Noboru, and Beth Levine. "Autophagy in Mammalian Development and Differentiation." Nature Cell Biology 12.9 (2010): 823-30. Nature Publishing 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Nix (gene)」の詳細全文を読む
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